For many species that reproduce sexually, how sex is expressed at different points across lifespan is highly contingent and dependent on various environmental factors. For example, in many species of fish, environmental cues can trigger a natural process of sex transition where a female transitions to male. For many species of turtle, incubation temperature influences the likelihood that turtle eggs will hatch males or females. What is the case for Homo sapiens? Is human sex expression influenced by contingent environmental factors (...) like we see in fish and turtles, with whom we share common ancestry and DNA? Our paper explores the current biological science of sex determination and how it applies to philosophical and theological accounts of the human person. We argue that while human sex determination is not susceptible to environmental cues to the same degree we see in other species, there is sufficient variability among the pathways of human sex development to complicate simplistic biological categories of male and female. (shrink)

Critical care of neonatesThe recently published report of the Nuffield Council on Bioethics, Critical care decisions in fetal and neonatal medicine, is a valuable contribution to the discussion of decision making in the critical care of neonates. Drawing upon medical evidence, the working party highlights the many practical difficulties arising in neonatal care and by setting out clearly the nature of the ethical and other issues arising in this area of medicine, and their relationship with neonatal development, the resulting report (...) has the potential to lead both to improved practice and to better informed communication between doctors and families when they face difficult decisions about how best to treat very premature babies. Based on medical evidence, the working party sets out guidelines on decision-making about the resuscitation of babies born before the gestational age of 25 weeks and 6 days, dividing this period into four chronological periods: before 21 weeks and 6 days when resuscitation should normally only take place within the context of a research project; between 22 weeks and 23 weeks when resuscitation should not normally be carried out unless the parents request it; at 23 or 24 weeks when parental views should take precedence; and, after 24 weeks when resuscitation should be the norm unless not in the child’s best interests.There are several practical ethical difficulties with this aspect of the advice. To what extent, for example, does the paediatric assessment of the child, intended to play a role in decision-making about the appropriateness of resuscitation, itself depend on the initiation of resuscitation? To what extent is it reasonable and humane to expect parents to take full responsibility for making decisions about resuscitation between 23 and 24 weeks? On what grounds is it acceptable to attempt to resuscitate a baby <21 weeks and 6 …. (shrink)

From a gender perspective, female immigrant domestic caregivers have been particularly impacted during the COVID-19 pandemic: first, as female immigrants, and second, due to their work within the domestic care sector, which has been so badly affected in this pandemic. This study investigates the emotions and experiences of 15 female Latin American immigrant domestic workers, caregivers in five Andalusian cities who were cohabiting with their employees/patients during the COVID-19 pandemic lockdown, using qualitative research through in-depth interviews and life stories. The (...) results show the moral debt accrued by the caregivers with the family who employ them, while worsening the physical and psychological health of many of the caregivers, due to both work overload and fear of the global pandemic. (shrink)

Two facets of diagnostic reasoning related to scientific thinking are recognizing the difference between confounded and unconfounded evidence and selecting appropriate interventions that could provide learners the evidence necessary to make an appropriate causal conclusion (i.e., the control-of-variables strategy). The present study investigates both these abilities in 3- to 6-year-old children (N= 57). We found both competence and developmental progress in the capacity to recognize that evidence is confounded. Similarly, children performed above chance in some tasks testing for the selection (...) of a controlled test of a hypothesis. However, these capacities were unrelated, suggesting that preschoolers’ nascent understanding of the control-of-variables strategy may not be driven by a metacognitive understanding that confounded evidence does not support a unique causal conclusion, and requires further investigation. (shrink)

Zu keiner Zeit hat Potsdam auf die europäische Kultur einen größeren Einfluss ausgeübt als im 18. Jahrhundert, als Friedrich der Große, der Philosophenkönig, den Absolutismus und die Aufklärung miteinander in Einklang zu bringen versuchte. Seit dem Beginn des 18. Jahrhunderts setzte der Aufstieg des Bürgertums in Verbindung mit den neuen Ideen der Aufklärung das höfische Monopol immer stärker unter Druck. Friedrich der Große nahm die Herausforderung an und wollte als König und Bürger der Leserepublik, als Herrscher und Intellektueller, Macht und (...) Geist zueinander führen. Der Hof in Potsdam, die Residenz am Rande der Metropole, wurde zum Ort dieses komplexen und spannungsreichen Rollenspiels, in dem die alte Welt der ererbten Herren und die neue Welt der kritischen Bürger ihre Grenzen auslotete. Das geschah unter den Augen Europas. Denn Friedrich der Große hatte dem Experiment Potsdam von Anfang an einen europäischen Rahmen gegeben. In Potsdam traf sich und auf Potsdam blickte die aufgeklärte Intelligenz aus ganz Europa. Die deutschen Aufklärer betrachteten das Rollenspiel vor den Toren Berlins dagegen skeptischer, weil sie der kulturellen Konstellation misstrauten und der europäische Hof quer lag zum großen Ziel einer deutschen Nationalkultur, für die der Philosoph von Sans-Souci so wenig Sinn zeigte. (shrink)

The dire implications of navigating the overwhelming whiteness of the education system for Black women is foregrounded by the author’s autoethnography about her educational journey and experiences. Within it, the author illustrates the key role of her Black identity - despite being immersed in whiteness– to provide a strong sense of self, pride and resilience, which ultimately leads to her survival in the unequal spaces of the education system. By way of her own educational experiences, the author shares how she (...) becomes motivated to embark upon a PhD as a way to centre and affirm Black identities and in order to make palatable spaces within the hostility of whiteness. Drawing on her PhD research, which is framed by Black feminist epistemology, Critical Race Theory and Bourdieu’s theory of practice, her findings, based on the semi-structured interviewing of 25 other Black British women graduates, illustrates that the participants share similar educational experiences and responses. The paper concludes by asserting that the attainment of Black girls and young women often does not reflect their strong commitment to education- which evidences one consequence of journeying into the ‘heart of whiteness'. Therefore, the author argues for the necessity of more research and support for this diverse group. (shrink)

Gangestad & Simpson make a major contribution by highlighting the importance of mate choice for good genes, the costs of alternative strategies, and tradeoffs inherent in human mating. By downplaying sex differences and ignoring the nongenetic adaptive benefits of short term mating, however, they undermine their goal of “strategic pluralism” by presenting a theory devoid of many documented complexities of human mating.

This is a review and discussion of Ask Vest Christiansen’s book Gym Culture, Identity and Performance-Enhancing Drugs: Tracing a Typology of Steroid Use. As indicated by the title, the book...

The writings of Stanley Cavell and Jacques Derrida share many points of intersection. One of these is their mutual interest in Shakespeare’s Hamlet; another is their assessments of J.L. Austin’s philosophy, and his concept of performativity. In this paper, we demonstrate that Cavell’s and Derrida’s respective essays on Hamlet offer a surprising insight into their views on Austin’s notion of performativity. Since Hamlet abounds with oaths and promises, testimonies and bearing witness, what is surprising is not that these philosophers should (...) have identified this theme but rather how they respond to it. We show that Derrida’s writings on Hamlet repeatedly draw and depend on the idea of performativity, amounting to a rapprochement with Austin’s concept; and we also show that Cavell questions the effectiveness of performatives in the play, in ways that sometimes resemble Derrida’s invocation of spectrality in the play. (shrink)

This is a review and discussion of Ask Vest Christiansen’s book Gym Culture, Identity and Performance-Enhancing Drugs: Tracing a Typology of Steroid Use. As indicated by the title, the book...

Mental health among students is one of the major concerns amidst the pandemic. Employing a correlational design, this study investigates the relationship between emotional intelligence and mental health among 152 senior high school students. Based on the statistical analysis, the r coefficient of 0.82 indicates a high positive correlation between the variables. The p-value of 0.00, which is less than 0.05, leads to the decision to reject the null hypothesis. Hence, a significant relationship exists between emotional intelligence and mental health (...) among senior high school. Implications were discussed in the study. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Ideas 63.4 (2002) 599-617 [Access article in PDF] Thinking Geometrically in Pierre-Daniel Huet's Demonstratio evangelica (1679) April G. Shelford Sometime after 1679, Pierre-Daniel Huet (1630-1721) indulged an author's vanity by comparing his Demonstratio evangelica with works whose authors are far better known today. He recorded his judgments on a scrap of paper. 1First, he contrasted the Demonstratio to Antoine Arnauld's Les nouveaux élémens (...) de géometrie (1664). While Arnauld had assumed that all the principles of geometry were true and all geometrical demonstrations certain, and had considered religious questions not amenable to methodical demonstration, Huet noted, "I made clear the contrary by proving religion through a methodical sequence of propositions similar to those one finds in geometry." For Arnauld religious belief fell into the class of things better proven through a series of mutually reinforcing propositions than through proofs modeled on geometry; Huet had actually accomplished the latter. Arnauld did not require geometric proofs in religious works; Huet wrote the Demonstratio "to satisfy those who do." Indeed, Arnauld forbade such proofs, "but I permitted them... and I proposed something to satisfy those who do [demand them]."Huet then considered Blaise Pascal's Pensées (1670). Pascal had also rejected demonstration in proving religious truths, Huet noted, opting instead for "moral proofs, which are directed more to the heart than to the mind. In other words he desired to work harder at moving and disposing the heart than at convincing and persuading the intellect." Apparently, "M. Pascal did not believe that one could prove the truth of the Christian religion by geometric proofs; much less that he had any hope of doing so." [End Page 599]Huet's jottings precisely situate the Demonstratio evangelica (1679)between the claims of Cartesian rationalism and Pascal's fideism and religion of the heart, inviting us to take another look at an imperfectly understood work. Scholarly treatment of the Demonstratio has generally been cursory or partial because it has been considered less for its own merits than for how it fits into larger research agendas. 2 Some scholars have offered important insights but either do not develop them or do not consider the Demonstratio in a sufficiently broad context. 3 A consensus on the Demonstratio's general thrust thus masks puzzling questions. Everyone acknowledges, for example, that Huet's apologetic responded to Baruch Spinoza's Tractatus theologico-politicus (1670). Like other Christian apologists, he had to maintain "the Mosaic authorship" that was "the supposed guarantee of the truth of the text," 4 devoting "long chapters to the authenticity of the books of the Old Testament." 5 Yet Huet began the Demonstratio with an assault on geometrical knowledge and an epistemological discussion—an odd place to begin refuting the Tractatus. 6 Why? The question deserves a good answer, as Huet was a scholar of international reputation, and his contemporaries judged the Demonstratio an important work. 7More important for us, the evolution of the Demonstratio superbly reflects a vanished intellectual world and scholarly culture and in fact records change [End Page 600] in that world over four decades. Its genesis was the rash promise of a young man inspired by the possibilities of geometry and aspiring to recognition in the Republic of Letters, but before fulfilling that promise Huet developed a lively interest in such diverse fields as biblical criticism and natural philosophy, and he would apply the insights gained there in his apologetic. 8 A central question confronting Huet and his contemporaries was how to achieve certainty in matters religious, historical, and scientific. 9 The Demonstratio reveals Huet's conclusion that certainty in all three was profoundly interrelated. Finally, he composed the Demonstratio during the 1670s, having grasped with much alarm the consequences of the spread of Cartesianism. Thus, the Demonstratio is an intellectual biography not just of the author but of an era.Of course, Huet had to contend with Spinoza's challenge to Mosaic authorship, which fatally undermined the historical certainty of the Bible, but he also wrote... (shrink)

Merab Konstantinovich [Mamardashvili] met with me immediately, as soon as I requested it, although he forewarned me that he could only dimly remember much of that distant past in which I was most interested. But evidently that past still perturbed him as well, since he agreed to speak with me even though he had not yet completely recovered from his illness, and hence his voice was feeble, at times subsiding to a whisper; he would pronounce his words indistinctly, constantly sticking (...) one onto another; on top of that, for technical reasons the dictaphone was situated a bit away from him. It was therefore very difficult to transcribe the text, and I raised many questions with the idea of asking Merab Konstantinovich about them at our next meeting and clearing up some things. But alas, there was no next meeting … Hence I am permitting myself now to publish only some of the most clearly enunciated fragments of my conversation with him, one of the four "forefathers" of the Moscow Methodological Circle, whose name for us, today's participants (and hence neophytes) in the methodological movement, is enveloped by legends handed down by word of mouth. I kept my questions to a minimum. Mamardashvili's reminiscences, arguments, and reflections will seem contentious to many. But no matter, one can dispute points of substance even with those who have passed on. (shrink)

The revolutionary restructuring of the whole of the life of our society, which got under way in the country after the April 1985 Plenum of the Central Committee of the CPSU, is inseparably bound up with a consolidation of the moral foundations of socialist society and the Soviet mode of life. A profound intellectual conviction, the greatest political and moral responsibility for the fate of the country, and an unwavering observance of the Leninist ethics of Bolshevism are the demands (...) now being placed on all Soviet people, but with special urgency on Party members. A concern for the moral purity and honesty of Communists is the prime duty of a Party organization. The Party calls for a most merciless struggle against accommodators, careerists, and opportunists, and against protectionism, family favoritism, nepotism, and promotion of workers on the basis of hometownism and personal loyalty. Party organizations must apply the full rigor of the requirements of the Party statutes to those who compromise the name of Party member and Soviet leader by violating Party duty, the commission of crimes of office, greed, economic featherbedding, and moral dereliction. (shrink)

It is a familiar story that on April 5, 56 B.C., Cicero made a motion in the Senate concerning Caesar's Campanian land law, and that this action of his was one of the reasons for the conference of Luca. Query: What were the terms of the motion?

The Human Tissue Act 2004 is designed to regulate the storage and use of organs and tissues from the living, and the removal, storage and use of the same material from the deceased. It repeals much criticized legislation, including the Human Tissue Act 1961, and establishes a Human Tissue Authority to ensure compliance with the Act via a licensing and monitoring regime. When the Act comes into force, probably in April 2006, it will be a criminal offence not to (...) comply with certain provisions of the Act, and a new offence of DNA 'theft' will be introduced. Importantly, the Act places consent at the centre of the system, both from the living and from or on behalf of the deceased. (shrink)

Objective: Ethical guidelines are designed to ensure benefits, protection and respect of participants in clinical research. Clinical trials must now be registered on open-access databases and provide details on ethical considerations. This systematic survey aimed to determine the extent to which recently registered clinical trials report the use of standard of care and post-trial obligations in trial registries, and whether trial characteristics vary according to setting. Methods: We selected global randomized trials registered on http://www.clinicaltrials.gov and http://www.controlled-trials.com. We searched for intervention (...) trials of HIV/AIDS, malaria, and tuberculosis from 9 October 2004, the date of the most recent version of the Helsinki Declaration, to 10 April 2007. Results: We collected data from 312 trials. Fifty-eight percent (58%, 95% CI = 53 to 64) of trial protocols report informed consent. Fifty-eight percent (58%, 95% CI = 53 to 64) of trials report active controls. Almost no trials (1%, 95% CI = 0.5 to 3) mention post-trial provisions. Most trials measure surrogate outcomes. Twenty percent (20%, 95% CI = 16 to 25) of trials measure patient-important outcomes, such as death; and the odds that these outcomes are in a low income country are five times greater than for a developed country (odds ratio (OR) 5.03, 95% CI = 2.70 to 9.35, p = < 0.001). Pharmaceutical companies are involved in 28% (CI = 23 to 33) of trials and measure surrogate outcomes more often than nonpharmaceutical companies (OR 2.45, 95% CI = 1.18 to 5.09, p = 0.31). Conclusion: We found a large discrepancy in the quality of reporting and approaches used in trials in developing settings compared to wealthier settings. (shrink)

n April, 2014 I organized an International Workshop on East-West Approaches to the Nature of Mind, Consciousness and Self, in the beautiful grounds of Dartington Hall, in Devon, England to explore the edges of current understanding of ordinary and extra-ordinary conscious experience. Although Consciousness Studies is now a flourishing area of investigation, ordinary and extra-ordinary human experiences do not fit comfortably into the prevailing materialist-reductionist paradigm, suggesting the need to explore non-reductionist approaches in an open, but nevertheless rigorous way. (...) Consciousness has, of course, also been studied in the East over the millennia, but there are major cultural differences in the ways mind, consciousness and self are conceptualized and investigated in the East and in the West, making it difficult to integrate Eastern with Western ways of thought. This provided the purpose for the workshop—to gather together an invited selection of some of the best current thinkers and researchers in this cross-disciplinary area to present their work, along with a group of discussants that included equally senior, mid-career and more junior researchers from different traditions (both Eastern and Western), to explore the issues in depth, with the aim of moving closer to a more integrated, inclusive worldview. The progression of the workshop over four days broadly followed four themes: 1) how to obtain knowledge additional to that provided by the usual third-person methods of science through subjective ways of knowing and by focusing close attention on the details of ordinary experience 2) the range and significance of extraordinary experiences 3) the potentially transformative effects on the knower of engaging in such explorations, and 4) some integrative ways of thinking about what is revealed by such investigations. (shrink)